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Fig. 7 | Nanoscale Research Letters

Fig. 7

From: Peptide-Mediated Tumor Targeting by a Degradable Nano Gene Delivery Vector Based on Pluronic-Modified Polyethylenimine

Fig. 7

Competition inhibition assay of polyplexes. a The cellular uptake of Pluronic-PEI/DNA-cy-3 complexes in HeLa, HepG2, and NIH 3T3 cells pretreated with DR5 was examined by fluorescence microscopy (scale bar: 200 μm). b Relative uptake efficiency of different polyplexes after treatment with inhibitor (DR5) in cells. Cellular uptake without any inhibition was used as control (mean ± SD, n =3). c The cellular uptake of Pluronic-PEI-DR5-TAT/DNA-cy3 complexes in HeLa, HepG2, and NIH 3T3 cells pretreated with DR5 was examined by fluorescence microscopy (scale bar: 200 μm). d Relative uptake efficiency of different polyplexes after treatment with inhibitor (DR5) in cells. Cellular uptake without any inhibition was used as control (mean ± SD, n = 3). Significance: **P < 0.01

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