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Table 2 Regression coefficients of the quadratic equations in optimization experiment

From: Liquid Crystalline Nanoparticles as an Ophthalmic Delivery System for Tetrandrine: Development, Characterization, and In Vitro and In Vivo Evaluation

Parameters

Regression coefficient

EE (%)

p

DL (%)

p

A 0

80.90

 

0.94

 

A 1

3.33

<0.001

0.27

<0.001

A 2

1.48

0.026

−0.09

<0.001

A 3

−0.54

0.365

−1.07 × 10−3

0.953

A 4

0.22

0.770

5.00 × 10−3

0.831

A 5

0.22

0.899

−2.50 × 10−3

0.299

A 6

−0.10

0.775

−0.03

0.915

A 7

1.70

0.012

0.06

0.009

A 8

−1.46

0.024

−6.59 × 10−3

0.706

A 9

−0.61

0.293

0.01

0.529

r

92.85

 

98.26

 

p

0.0028

 

<0.0001

 
  1. A 0A 9 are the regression coefficients of the respective variables. The r-value was used as a quality indicator to evaluate the fitness of the second-order polynomial equation. The p value less than 0.05 was considered to be statistically significant

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