Fig. 2
From: Synergistic Effects of Gold Nanocages in Hyperthermia and Radiotherapy Treatment
Immunocytochemistry and cellular uptake of the GNCs. a Immunocytochemistry for the negative control group of 4T1 cells. b Selective immunohistochemical staining of CD44 within the 4T1 cells. c Uptake of GNCs, PEG-GNCs versus CD44-PEG-GNCs per kilogram of 4T1 cells, as measured by ICP-MS. d (1–2) TEM images of 4T1 cells incubated with CD44-PEG-GNCs, and the CD44-PEG-GNCs entered the cells through receptor-mediated endocytosis. d (3) CD44-PEG-GNCs readily aggregated around the organelle membranes. d (4) CD44-PEG-GNCs aggregated in the organelles