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Fig. 3 | Nanoscale Research Letters

Fig. 3

From: Tissue Plasminogen Activator Binding to Superparamagnetic Iron Oxide Nanoparticle—Covalent Versus Adsorptive Approach

Fig. 3

Physical properties of tPA particles. a Hydrodynamic diameter of covalent functionalized SPIONs measured at t = 60 s after ultrasonication correlates with the used tPA amount. Size increase is significantly higher (p < 0.005) for activated particles. b Hydrodynamic diameter of covalently functionalized SPIONs (c(tPA) = 500 μg/mL) is dependent on the reaction time (DLS). c Grafting of tPA significantly influences surface properties of PAM-SPIONs at c(tPA) = 250 μg/mL

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