Fig. 7
Antiviral effect of different liposomal formulations and free dapivirine. a Dose-response curves for the antiviral effect of different liposomal formulations and free dapivirine. b Comparison of calculated EC50 of each liposomal formulation and free dapivirine. Liposome preparations were pre-incubated with TZM-bl cells for 2 h before virus was added and incubated for 48 h. Values are means ± standard deviations of three replicate measurements in one representative experiment of three independent experiments. *From one-way ANOVA, significant differences (p < 0.001) in EC50 were observed between free dapivirine and the liposomal dapivirine. Dapi: dapivirine