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Table 1 Characterisation of the immunoliposomes

From: Inhibition of HIV Virus by Neutralizing Vhh Attached to Dual Functional Liposomes Encapsulating Dapivirine

Liposome PC conc. (mg/ml)a Dapivirine (μM) No. of Vhh molecules per liposome Vhh (μg/ml) Diameter (nm)a Zeta potential (mV)a
Lipo1-lab5 11.937 ± 0.001 160 126.3 228.0 ± 1.0 −45.0 ± 0.9
Lipo1-J3 11.708 ± 0.008 160 118.4 223.4 ± 4.5 −37.4 ± 0.5
Lipo2-lab5 5.974 ± 0.005 95 150.0 130.9 ± 1.4 −38.7 ± 0.7
Lipo2-J3 6.149 ± 0.003 108 159.9 131.2 ± 1.9 −38.5 ± 0.2
Lipo2-dapi 6.478 ± 0.001 6.5 122.9 ± 1.8 −46.0 ± 0.9
Lipo2-dapi-J3 5.548 ± 0.002 5.5 125 169.6 123.4 ± 1.8 −38.5 ± 0.4
Lipo3 control 7.573 ± 0.003 130.9 ± 1.7 −42.5 ± 0.4
Lipo3-J3 6.456 ± 0.004 121 168.2 142.2 ± 3.2 −36.4 ± 0.4
Lipo3-dapi 6.675 ± 0.003 6.7 128.2 ± 2.6 −41.7 ± 0.5
Lipo3-dapi-J3 6.806 ± 0.001 6.8 108 157.0 139.1 ± 1.8 −37.8 ± 0.6
  1. Dapi: dapivirine
  2. aData are means ± standard deviations of three replicate measurements in one representative experiment of three independent experiments