Table 1 The performance of SiNW FET biosensors
From: Recent Advances in Silicon Nanowire Biosensors: Synthesis Methods, Properties, and Applications
Device specification | Fabrication | Mechanism | Application | Detection limit |
|---|---|---|---|---|
p-Type SiNW, diameter: 20 nm | Bottom–up | Biotin–avidin binding | Streptavidin | 10 pM |
n-Type SiNW, p-type SiNW, diameter 20 nm | Bottom–up | Antibody–antigen interaction | PSA, CEA, Mucin-1 | PSA 2 fM, CEA 0.55 fM |
p-Type SiNW, diameter 20 nm; p-type SiNW, diameter 20 nm | Bottom–up | PNA–DNA hybridization | DNA | 10 fM |
p-Type SiNW, diameter 20 nm | Bottom–up | Antibody–virus interaction | Influenza A virus | Single virus |
n-Type SiNW, p-type SiNW, thickness 40 nm, width 50–150 nm | Top–down | Biotin–avidin binding | Streptavidin | 10 fM |
n-Type SiNW, p-type SiNW; thickness 40 nm, width: 50–150 nm | Top–down | Antibody–antigen interaction | PSA, CA 15.3 | PSA 2.5 ng/mL |
n-Type SiNW, p-type SiNW, width 20 nm, length 30 nm | Top–down | DNA–DNA hybridization | DNA | 10 pM |
n-Type SiNW, p-type SiNW, width 50 nm, length 20 nm | Top–down | DNA–DNA hybridization | DNA | 25 pM |
n-Type SiNW, thickness ≤40 nm | Top–down | Antibody–antigen interaction | PSA | 30 aM |
p-Type SiNW, diameter 30–60 nm | Bottom–up | Protein–protein interaction | TnI | 7 nM |
n-Type SiNW, width 50 nm, thickness 60 nm, length 100 nm | Top–down | PNA–DNA hybridization | DNA | 10 fM |
n-Type SiNW, width 50 nm, thickness 60 nm, length 100 nm | Top–down | Antibody–antigen interaction | cTnT | Ifg/mL |
n-Type SiNW, width 50 nm, thickness 60 nm, length 100 nm | Top–down | PNA–DNA hybridization | RT-PCR product of DEN-2 | 10 fM |
n-Type SiNW, width 50 nm, thickness 60 nm, length 100 nm | Top–down | PNA–RNA hybridization | microRNA | 1 fM |
n-Type SiNW, width 50 nm, thickness 60 nm, length 100 nm | Top–down | Protein–DNA interaction | ER | 10 fM |
n-Type SiNW, width 50 nm, thickness 60 nm, length 100 nm | Top–down | Antibody–antigen interaction | cTnT, CK-MM, CK-MB | 1 pg/mL |