Fig. 5
From: A Protein Nanopore-Based Approach for Bacteria Sensing
Original current recordings showing reversible current blockage events induced by the association of P. aeruginosa (P.a.) (a) and E. coli (E.c.) (b), respectively, with the α-HL, in the presence of a synthetic antimicrobial peptide (CMA3) added on the trans chamber at a bulk concentration of 20 μM, at ΔV = −80 mV. In c and d, we show the corresponding scatter plots of current blockade versus dwell time of blockade events reflecting the P.a. and E.c. interaction with the α-HL pore in the presence of the peptide. The distinct states of the nanopore, i.e., free and temporarily blocked by a bacterium, are denoted in c