Fig. 4
From: Hepatotoxicity and Drug/Chemical Interaction Toxicity of Nanoclay Particles in Mice
Effect of nanoclay particles (NC) on paraquat (PQ)-induced toxicity. Mice were injected intraperitoneally with PQ at 50 mg/kg together with intravenous injection of vehicle or NC (5 mg/kg). a At 24-h post-injection, serum levels of the liver enzymes alanine aminotransferase (ALT, open bars) and aspartate aminotransferase (AST, solid bars) were determined using commercially available kits (see Methods). b Plasma levels of blood urea nitrogen (BUN). Data are representative of three independent experiments and are presented as mean ± standard error of the mean (n = 4). Significant difference (*P < 0.05, **P < 0.01) between vehicle- and PQ-treated groups