Fig. 5
From: Hepatotoxicity and Drug/Chemical Interaction Toxicity of Nanoclay Particles in Mice
Effect of nanoclay particles (NC) on cisplatin (CDDP)-induced toxicity. Mice were injected intraperitoneally with CDDP at 80 μmol/kg together with intravenous injection of vehicle or NC (5 mg/kg). a At 24-h post-injection, serum levels of the liver enzymes alanine aminotransferase (ALT, open bars) and aspartate aminotransferase (AST, solid bars) were determined using commercially available kits (see Methods). b Plasma levels of blood urea nitrogen (BUN). Data are representative of three independent experiments and are presented as the mean ± standard error of the mean (n = 4). Significant difference (**P < 0.01) between the vehicle- and CDDP-treated groups