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Fig. 6 | Nanoscale Research Letters

Fig. 6

From: A Novel Solubility-Enhanced Rubusoside-Based Micelles for Increased Cancer Therapy

Fig. 6

The anti-cancer effects of RUB-based micelles on MCF-7 cells. a Apoptosis of MCF-7 cells treated with indicated formulations of CUR (23 μM) and RES (110 μM) for 24 h was analyzed by flow cytometry using Annexin V-FITC/PI staining. b Cell viability of MCF-7 cells was measured by MTT method, which was treated with indicated formulations of CUR (23 μM) and RES (110 μM) for 24 h. c, d Time- and dose-dependent manners of cell viability of MCF-7 cells treated with indicated formulations were measured by MTT method. c represented for CUR (23 μM). RES’ concentration was 110 μM. e In vitro release profile of CUR and RES from RUB/CUR + RES micelles and RUB/CUR micelles + RUB/RES micelles in PBS buffer (pH 7.4). Error bars indicated s.d. (n = 3). ***P < 0.001 (two-tailed Student’s t test)

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