Table 1 Physicochemical properties of γ-PGA-coated Dox lipoplexes (n = 3)
Formulation | The concentration of γ-PGA (%w/v) | Particle size (nm) | PI | Zeta potential (mV) | EE (%) |
|---|---|---|---|---|---|
L-Dox | – | 188.3 ± 23.5 | 0.204 ± 0.053 | 24.4 ± 5.3 | 92.4 ± 5.6 |
PGA-L-Dox | 0.025 | 205.2 ± 28.7 | 0.248 ± 0.039 | 8.2 ± 4.0 | 90.7 ± 5.2 |
0.1 | 226.5 ± 43.1 | 0.258 ± 0.061 | −27.8 ± 5.4 | 91.6 ± 4.7 | |
0.25 | 239.5 ± 74.6 | 0.276 ± 0.085 | −39.8 ± 7.5 | 88.3 ± 4.9 |