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Fig. 9 | Nanoscale Research Letters

Fig. 9

From: Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration

Fig. 9

CD44-positive cell distribution in the rat cochlea exposed to liposome nanocarrier demonstrated using immunofluorescent confocal microscopy. CD44-positive cells were mainly detected in the stria basal cell (SBC), spiral ligament (SL), Dieter’s cells (DC), spiral ganglion cell (SGC), and capillary endothelial cell (CEC) in the groups of negative control (H2O) (ae), empty liposome nanocarriers (LPN) (fj), and Gd-DOTA-containing LPN (LPN + Gd) (kn). There was no staining in the antibody omitted negative control (AbNC) (o). IHC inner hair cells, M-CEC capillary endothelial cell in modiolus, SL-CEC capillary endothelial cell in spiral ligament: spiral ganglion cells, SL-III spiral ligament fibrocyte type III, SL-IV spiral ligament fibrocyte type IV, TM tectorial membrane, OHC outer hair cells. Scale bar = 16 μm

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