Table 2 Tumorigenic activity of total population, isolated CD44+ and CD44– EC fractions
Groups | Introducible dose of EC cells | Administration of total population of EC cells | Administration of CD44+ EC cell fraction | Administration of CD44– EC cell fraction |
---|---|---|---|---|
Total number of EC cells in the peritoneal cavity (×107) when administering under various concentrations | 3 × 106 | 35.80 ± 1.27 | 826.51 ± 6.53* | 7.82 ± 0.94* |
3 × 105 | 3.00 ± 0.25 | 65.00 ± 1.27* | – | |
3 × 104 | – | 13.50 ± 0.31 | – | |
3 × 103 | – | – | – | |
Number of animals with EC development to day 7 after administration of various concentrations of cells | 3 × 106 | 10/10 | 10/10 | 5/10 |
3 × 105 | 5/10 | 9/10 | 0/10 | |
3 × 104 | 0/10 | 3/10 | 0/10 | |
3 × 103 | 0/10 | 0/10 | 0/10 |