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Fig. 4 | Nanoscale Research Letters

Fig. 4

From: Successive Release of Tissue Inhibitors of Metalloproteinase-1 Through Graphene Oxide-Based Delivery System Can Promote Skin Regeneration

Fig. 4

In vivo experiment. a Scheme and the SDS and model. b Histologic and immunohistochemical analysis in vivo (1 cm). Continuous collagen fiber is visible in the TIMP-1-GO group. c Quantitative assessment revealed significant differences between control and GO compared with TIMP-1 and TIMP-1-GO (p < 0.05). The hair follicles of different groups were significantly different (p < 0.05). Skin defects treated with TIMP-1 showed significant differences with control group and GO group by semi-quantitative (p < 0.05)

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