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Table 4 Comparison of the developed method of deposition of PPD membrane with previously reported methods

From: Improvement of amperometric transducer selectivity using nanosized phenylenediamine films

Optimal method of PD polymerization

Type of electrode

Optimal isomer of PD

Duration of the electrode preparation

Effectiveness of blocking properties

Storage stability

Biosensor application

Ref.

CV (from − 0.3 V to +0.9 V vs. Ag/AgCl)

Pd disk

m-PD

48 min

Full blocking of AA, cys, acetaminophen.

Small interference from UA

N/A

N/A

[8]

Constant potential (+0.7 V vs. Ag/AgCl)

Ru-covered carbon fiber ME

m-PD

45 min

Full blocking of UA, cys, acetaminophen, DA.

Small interference from AA—addition of ascorbate oxidase to remove it

> 2 days

Glucose, lactate and glutamate biosensors, in vivo analysis in rat brain

[6]

Constant potential (+0.7 V vs. SCE)

Pt–Ir cylinders ME

o-PD

15 min

Full blocking of AA

> 7 days

N/A

[7]

CV

(from −0.25 V to +0.9 V vs. SCE)

Glassy carbon electrode

o-PD

15 min

Full blocking of AA, UA and DA

> 15 days

N/A, H2O2 detection in human serum samples

[9]

Constant potential (+0.7 V vs. Ag/AgCl)

Pt cylinders ME

o-PD

15 min

Full blocking of AA

N/A

N/A

[13]

CV

(from 0 V to +0.9 V vs. Ag/AgCl)

Pt disk

m-PD

6 min

Full blocking of AA, cys, UA, DA

> 8 days

Human serum samples and cell lysate

This work

  1. ME microelectrode, AA ascorbic acid, cys cysteine, DA dopamine, UA uric acid, N/A not applicable

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