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Fig. 6 | Nanoscale Research Letters

Fig. 6

From: Promotion of SH-SY5Y Cell Growth by Gold Nanoparticles Modified with 6-Mercaptopurine and a Neuron-Penetrating Peptide

Fig. 6

The nanoparticle induced cell proliferation and neurite growth. a cell images at days 1, 2, 3, and 4. b Neurite lengths of 6MP-AuNPs-RDP-treated cells and the control. The values were averaged for 200 neurites. **p < 0.01 compared with the control. c Metabolic activity of 6MP-AuNPs-RDP-treated cells. The cells received treatment three times once a day for 3 days. At the first time, 6MP-AuNPs-RDP was added into the cell media after the cells were cultured for 24 h from cell transplantation. Each concentration of the particles was 0.25 μg/mL. d Images of neurite growth of the cells on surface coating with 6MP-AuNPs-RDP. 6MP-AuNPs-RDP was plated on the bottom of culture dishes of 3.5 cm diameter, and then, the cells were transplanted on the dishes. e The neurite length were measured at 0 ~ 3 days. The cells with only solvent were used as control. The values were averaged for 200 neurites. **p < 0.01 compared with the control, *p < 0.05, **p < 0.01 compared with the cells of day 1. The blue arrow points to the representative neurites

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