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Table 2 The permeation of 5-FU in human hypertrophic scar in vitro at different time points

From: Experimental Study of 5-fluorouracil Encapsulated Ethosomes Combined with CO2 Fractional Laser to Treat Hypertrophic Scar

n = 6

1 h

3 h

6 h

10 h

16 h

24 h

5E

 Mean

0.73

1.21

3.3

7.54

11.34

20.73

 STD

0.33

0.33

0.59

1.55

2.03

3.77

5EL

      

 Mean

4.15

18.64

55.41

85.66

98.8

107.61

 STD

2.22

8.24

11.38

12.91

14.75

13.27

  1. mean ± SD; 5EL: the enthosomal gels encapsulated with 5-FU combined with CO2 fractional laser, n = 6; 5E: the enthosomal gels encapsulated with 5-FU, n = 6

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