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Fig. 6 | Nanoscale Research Letters

Fig. 6

From: Investigation on Physicochemical Characteristics of a Nanoliposome-Based System for Dual Drug Delivery

Fig. 6

Transmission electron microscopy (TEM) and selected area electron diffraction (SAED) analyses of dual drug- or single drug-encapsulated nanoliposomes: ERL- and DOX-encapsulated nanoliposomes (scale bar, 200 nm) (a), a single nanoliposome containing ERL and DOX-sulfate complexes (scale bar, 50 nm) (b), a high resolution- (HR-) TEM image representing DOX-sulfate crystals present inside the nanoliposome and ERL crystals in an outermost region of the nanoliposome (sale bar, 10 nm) (c), a SAED pattern of DOX-sulfate crystals and ERL crystals present in a nanoliposome (d), a single nanoliposome encapsulated with ERL (scale bar, 50 nm) (e), a HR-TEM image representing small crystals of ERL and amorphous domains in an outermost region of the nanoliposome (sale bar, 10 nm) (f), a SAED pattern of ERL crystals present in an outermost region of the nanoliposome (g), a single nanoliposome encapsulated with DOX (scale bar, 100 nm) (h), a HR-TEM image representing crystalline lattices of DOX-sulfate inside the nanoliposome (sale bar, 5 nm) (i), and a SAED pattern of DOX-sulfate crystals present inside the nanoliposome (j)

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