Fig. 4
From: Aptamer-modified Magnetic Nanosensitizer for in vivo MR imaging of HER2-expressing Cancer
Binding affinity data of anti-HER2 aptamer (AptHER2-OH) thiolated anti-HER2 aptamer (AptHER2-SH) and AptHER2-MNS onto HER2 proteins by measuring the filter binding assay. a The schematic illustration showing the process of filter binding assay of aptamers. b The fraction bound aptamer graph against HER2 concentration. c The Kd value graph of AptHER2-OH (0.42 ± 0.05 nM, R2 = 0.99, p < 0.0001), AptHER2-SH (26.88 ± 8.24 nM, R2 = 0.98, p < 0.0001), and AptHER2-MNS (0.57 ± 0.26 nM, R2 = 0.91, p = 0.001) calculated from b. Error bars were represented by positive y-axis only