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Fig. 5 | Nanoscale Research Letters

Fig. 5

From: Synthesis and In Vitro Study of a Dual-Mode Probe Targeting Integrin αvβ3

Fig. 5

Confocal laser scanning microscopy (CLSM) images of A549, SUNE-1-5-8F, and MCF-10A cells. a Cellular immunofluorescence images of integrin αvβ3. A549 and SUNE-1-5-8F cell line expressed in the cell membrane, MCF-10A cells almost no expression of integrin αvβ3. b A549, SUNE-1-5-8F, and MCF10A cells incubated with cRGD-Gd-Cy5.5 at 200 μg mL−1 concentration at 37 °C for 1 h. The amount of probes bound to cells agrees with the results of cellular immunofluorescence. c Flow cytometry assay for detecting the integrin αvβ3 expressions in the A549, SUNE-1-5-8F, and MCF-10A cells

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