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Table 5 Addition of trehalose during homogenization (after lyophilization)

From: Lyophilized Hybrid Nanostructured Lipid Carriers to Enhance the Cellular Uptake of Verapamil: Statistical Optimization and In Vitro Evaluation

Formula code (Lipid:trehalose) ratio PS (nm) PDI % EE
VER-9 1:1 192.29 ± 2.98 0.553 ± 0.075 94.06 ± 2.55
VER-9 1:2 184 ± 3.84 0.694 ± 0.076 93.26 ± 2.66
VER-11 1:1 195.78 ± 4.58 0.568 ± 0.029 94.25 ± 1.57
VER-11 1:2 211.72 ± 3.13 0.760 ± 0.108 92.17 ± 1.67
  1. PS particle size, PDI polydispersity index, EE entrapment efficiency