Fig. 8
From: Zirconia Nanoparticles-Induced Toxic Effects in Osteoblast-Like 3T3-E1 Cells
TiO2 and ZrO2 NP-induced osteogenesis-related genes changes in 3T3 cells. After the 3T3-E1 cells were differentiated using mineralized solution for 3, 7, 14, and 21 d, accompanied with TiO2 and ZrO2 NPs at various concentrations. The osteogenesis-related gene changes were detected using RT-PCR. The results represent the means ± SEM of three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001, compared with the control