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Table 2 The percentages of rat glioma C6 cells for each level of genotoxicity after 3 h of treatment with the free form of compounds Les-3288 and Les-3833, and their complexes with the polymeric nanocarrier (PNC)

From: Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier

Sample	Comet class (% of cells)					DI
Sample	0	1	2	3	4	DI
Control	81.3 ± 0.5	18.6 ± 0.4				18.60 ± 0.35
Les-3288	81.3 ± 0.3	16.0 ± 0.2	2.6 ± 0.4			21.20 ± 0.52***
Les-3288+PNC	84.0 ± 0.1	12.0 ± 0.1	2.6 ± 0.4	1.3 ± 0.2		21.10 ± 0.23**
Les-3833	38.6 ± 0.3	60.0 ± 0.5	1.4 ± 0.2			62.80 ± 0.84***
Les-3833+PNC	8.0 ± 0.3	76.0 ± 2.9	13.3 ± 0.8	2.6 ± 0.3		110.40 ± 3.13***
PNC	84.0 ± 0.6	16.0 ± 0.1				16.00 ± 0.11
Dox	62.6 ± 0.4	36.0 ± 0.4			1.3±0.17	41.20 ± 0.40***

Damage index (DI): **P ≤ 0.01, ***P < 0.001 compared with untreated control cells

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