Table 1 Characterization of all liposomes
Liposomes | Particle size | PDI | Zeta potential | Encapsulation efficiency(%) | Drug-loading content (‰) | ||||
|---|---|---|---|---|---|---|---|---|---|
(nm) | (mv) | DOX | FIPI | TOS | DOX | FIPI | TOS | ||
Blank-lip | 88.58 ± 0.27 | 0.230 ± 0.004 | − 13.80 ± 0.66 | – | – | – | – | – | - |
DOX-lip | 84.53 ± 0.45 | 0.225 ± 0.005 | − 27.07 ± 0.38 | 96.83 ± 1.30 | – | – | 1.33 ± 0.01 | – | - |
FIPI-lip | 93.58 ± 0.43 | 0.220 ± 0.017 | − 31.63 ± 0.40 | – | 96.07 ± 1.85 | – | – | 8.76 ± 0.19 | - |
TOS-lip | 108.60 ± 0.75 | 0.187 ± 0.007 | − 50.33 ± 1.61 | – | – | 94.10 ± 0.03 | – | – | 66.92±0.67 |
DF-lip | 102.73 ± 1.16 | 0.243 ± 0.009 | − 27.97 ± 0.67 | 96.28 ± 2.50 | 94.80 ± 1.27 | – | 1.32 ± 0.03 | 8.86 ± 0.06 | - |
DT-lip | 108.40 ± 0.87 | 0.183 ± 0.016 | − 59.40 ± 1.22 | 94.58 ± 2.87 | – | 91.29 ± 2.84 | 1.19 ± 0.06 | – | 65.67±0.59 |
DFT-lip | 119.00 ± 0.80 | 0.188 ± 0.010 | − 58.50 ± 1.04 | 93.45 ± 3.71 | 91.46 ± 3.71 | 91.42 ± 1.94 | 1.19 ± 0.04 | 8.69 ± 0.19 | 65.16±0.18 |