Fig. 4From: Optimization and Evaluation of Pretreatment Method for sp-ICP-MS to Reveal the Distribution of Silver Nanoparticles in the BodySimultaneous quantification and physical property analyses of intravenously administered nAg100 and Ag+. nAg100 and Ag+ were intravenously administrated in mice (0.75 or 1.5 mg/kg). After 24 h, their livers and blood were collected. All samples were pretreated with NaOH solution. Ag concentration in a blood and b liver were measured by ICP-MS. nAg in c blood and d liver were measured by sp-ICP-MS. The average diameter of the particles detected in the liver is shown in e. The results are expressed as mean ± SE (n = 3)Back to article page