Table 5 A range of nanoparticle conjugates that have been examined for anticancer therapy
From: Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications
Type of nanoparticle | Size (nm) | Medical delivery application | Ref |
|---|---|---|---|
PEGylated AuNPs conjugated with TNF | 30–34 | Delivery of TNF to cancer cells targeted by the TNF itself, TNF induces cell apoptosis | [158] |
AuNPs conjugated with folic acid using a PEG linker | 10 | Delivery of folic acid (vitamin B9), a precursor for nucleic acid production | [159] |
AuNPs loaded with doxorubicin | 30–40 | Delivery of doxorubicin-loaded gold nanoparticles for tumor targeting/therapy | [160] |
AuNPs coated with a tumor specific uptake peptide | 25–40 | Drug delivery to lymphoma cells with gold nanoparticles conjugated with cellular uptake peptides specific to lymphoma cells | [161] |