Fig. 8
From: Impact of Gold Nanoparticles on Testosterone Metabolism in Human Liver Microsomes
Effects of 40 nm naked and PC AuNP on the production of 2β-OH TST (A1–A3), 6β-OH TST (B1–B3), 15β-OH TST (C1–C3), 16α-OH TST (D1–D3), 16β-OH TST (E1–E3), and AD (F1–F3); in three different single donor HLM (HDA1, HDB2, and HDC3). Means followed by the same letter were not significantly different for each nanoparticle (Tukey’s honest significant difference = 5%). Naked no PC, PC human plasma protein corona, HLM human liver microsomes, BPEI branched polyethylenimine, LA lipoic acid, PEG polyethylene glycol, 2β-OH TST 2β-hydroxytestosterone, 6β-OH TST 6β-hydroxytestosterone, 15β-OH TST 15β-hydroxytestosterone, 16α-OH TST 16α-hydroxytestosterone, 16β-OH TST 16β-hydroxytestosterone, AD androstenedione