Fig. 3
From: Potent anti-tumor immunostimulatory biocompatible nanohydrogel made from DNA
Detection of cytokines released from RAW264.7 cells stimulated with CpG-ODN, CpG-RCA gel, and CpG-MCA gels using ELISA-kit. a The secretion of TNF-α from RAW264.7 cells. b The secretion of TNF-α from RAW264.7 cells after treated with different concentrations of CpG-MCA gels. c Detection of the immuno-stimulating ability of CpG gels and non-CpG gels (R12-C, R4M4-C, and R4M8-C). d The secretion of IL-6 from RAW264.7 cells. e The secretion of IL-6 from RAW264.7 cells after treated with different concentrations of MCA gels. Results are expressed as the mean ± SD of two independent experiments. **P < 0.01, ***P < 0.001, ****P < 0.0001