Fig. 11
In vitro targeted photothermal assay. a Confocal microscopic images of calcein-AM/PI-stained SKBR3 cells in in different treatments groups (Her2-GPH NPs group, laser group, GPH NPs + laser group, Her2-GPH NPs + laser group) (scale bar = 100 μm). SKBR3 cells served as control. b Relative cell viabilities of SKBR3 cells in the five groups after treatment as shown in Fig. 11 a (data expressed as mean ± SD, *P < 0.05, ***P < 0.001, n = 4); c cell viabilities of SKBR3 cells incubated with Her2-GPH NPs at different concentrations (0, 50, 100, 150, 200 μg/mL) with or without NIR laser irradiation (808 nm, 1 W/cm2, 10 min) (data expressed as mean ± SD, *P < 0.05, ***P < 0.001, n = 4)