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Fig. 4 | Nanoscale Research Letters

Fig. 4

From: Graphene Oxide in a Composite with Silver Nanoparticles Reduces the Fibroblast and Endothelial Cell Cytotoxicity of an Antibacterial Nanoplatform

Fig. 4

Nanoplatforms coated with graphene oxide decreased the cytotoxicity of silver nanoparticles. Morphology of fibroblasts cultured on a non-coated nanoplatforms, b silver nanoparticle-coated nanoplatforms, c graphene oxide-coated nanoplatforms, d silver nanoparticles and graphene oxide composite-coated nanoplatforms. Morphology was assessed by light microscopy using phase contrast with × 200 magnification. Fibroblast (e) and HUVEC (f) viability after 24 h of incubation on the nanoplatforms was determined using a PrestoBlue assay. Values are expressed as mean ± standard deviation (n = 3, each experiment in triplicate). Statistical significance is indicated by different superscripts (one-way ANOVA; P < 0.05). Abbreviations: HUVECs, human umbilical vein endothelial cells; C, control group (foil without nanoparticles); AgNPs, nanoplatform coated with silver nanoparticles; GO, nanoplatform coated with graphene oxide; Ag-GO, nanoplatform coated with a composite of graphene oxide and silver nanoparticles; RU, relative units

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