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Fig. 1 | Nanoscale Research Letters

Fig. 1

From: Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis

Fig. 1

Abilities of MDSCs, macrophages, and DCs to uptake FMT. a Macrophages were treated with FMT (1000 ng/mL) for 24 h, then stained with Prussian blue to ascertain the cellular presence and deposition of iron among three groups: before magnetic separation, magnetically selected (FMT+), not magnetically isolated (FMT-). b Splenocytes from naïve C57BL/6 mice were incubated with FMT for 6 h, 12 h, 24 h, and 48 h. FACS analysis of the percentages of MDSCs, macrophages, and DCs in two subsets: before magnetic separation, FMT-positive cells. c The ratio of FMT-positive cells to cells before magnetic separation. All data are representative of three independent experiments for each experimental group and are displayed as the means ± standard deviation

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