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Fig. 5 | Nanoscale Research Letters

Fig. 5

From: RETRACTED ARTICLE: Upregulating MicroRNA-410 or Downregulating Wnt-11 Increases Osteoblasts and Reduces Osteoclasts to Alleviate Osteonecrosis of the Femoral Head

Fig. 5

Poor expression of Wnt-11 and overexpression of miR-410 alleviate pathological changes of rats tissues and restrain apoptosis of osteocytes. a Morphological observation of the femoral head of rats in each group (200 ×). b Ultrastructural observation of bone cells in rats of each group (8000 ×). c The results of TUNEL staining (200 ×). d Detection of apoptosis rate by TUNEL assay. e Detection of the Bax and Bcl-2 mRNA expression by RT-qPCR. f, g Detection of the Bax and Bcl-2 protein expression by western blot analysis. *P < 0.05 vs. the normal group. +P < 0.05 vs. the agomir-NC group. #P < 0.05 vs. the siRNA-NC group. &P < 0.05 vs. the agomir-miR-410 + OE-NC group

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