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Fig. 7 | Nanoscale Research Letters

Fig. 7

From: RETRACTED ARTICLE: Upregulating MicroRNA-410 or Downregulating Wnt-11 Increases Osteoblasts and Reduces Osteoclasts to Alleviate Osteonecrosis of the Femoral Head

Fig. 7

Highly expressed miR-410 and lowly expressed Wnt-11 elevate the expression of OCN, ALP, BGLAP, and CollĪ±1 as well as abate NTX-1, CTX-1, ACP5, CTSK, and MMP9 expression in ONFH rats. a Detection of osteogenesis and osteoclast function indices in the serum of rats in each group by ELISA. b Detection of osteoblast- and osteoclast-related genes by RT-qPCR. c, d Detection of osteoblast- and osteoclast-related genes protein expression by western blot analysis. *P < 0.05 vs. the normal group. +P < 0.05 vs. the agomir-NC group. #P < 0.05 vs. the siRNA-NC group. &P < 0.05 vs. the agomir-miR-410 + OE-NC group

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