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Fig. 8 | Nanoscale Research Letters

Fig. 8

From: RETRACTED ARTICLE: Upregulating MicroRNA-410 or Downregulating Wnt-11 Increases Osteoblasts and Reduces Osteoclasts to Alleviate Osteonecrosis of the Femoral Head

Fig. 8

Increased Wnt-11 and decreased miR-410 are found in ONFH tissues as well as Wnt-11 is the target gene of miR-410. a Prediction of binding sites of miR-410 on Wnt-11 3′UTR. b Luciferase activity detection for verifying the relationship between miR-410 and Wnt-11. c Detection of miR-410 and Wnt-11 expression by RT-qPCR. d, e Wnt-11 protein expression determined by western blot analysis. f Expression of Wnt-11 in femoral head of rats in each group detected by immunohistochemistry (200 ×). g Comparison of the positive rate of Wnt-11 protein expression in each group. *P < 0.05 vs. the normal group. +P < 0.05 vs. the agomir-NC group. #P < 0.05 vs. the siRNA-NC group. &P < 0.05 vs. the agomir-miR-410 + OE-NC group

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