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Fig. 8 | Nanoscale Research Letters

Fig. 8

From: Mesoporous Silica Nanoparticle–Based Combination of NQO1 Inhibitor and 5-Fluorouracil for Potent Antitumor Effect Against Head and Neck Squamous Cell Carcinoma (HNSCC)

Fig. 8

a In vivo antitumor efficacy of FNQ-MSN in HNSCC xenograft model. The mice bearing HNSCC tumors were treated with 5-FU, ß-lap, 5-FU+ß-lap and FNQ-MSN at a fixed dose of 5 mg/kg of 5-FU and 10 mg/kg of ß-lap intravenously for 3 times. Tumor volume was noted as a part of efficacy analysis and compared with non-treated control. b Body weight analysis corresponding to tumor volume data. *p < 0.05 and ***p < 0.001

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