Fig. 8

Apt-Au@MSL induced apoptosis in SGC-7901 cells. a SGC-7901 cells were treated with indicated concentrations of Apt-Au@MSL for 24 h. Then, the total protein was extracted and incubated with synthetic Apt-Au@MSL substrates for measuring caspase activities. Dose-dependent (b) and time-dependent (c) effects of Apt-Au@MSL on PARP and caspases expression. d, e Quantitative analysis of PARP, caspase-7, caspase-9, and caspase-3 expressions. Data are means ± SD, *P < 0.05, **P < 0.01