Fig. 5
a In vivo T2-MR images of normal and tumor subcutaneous tissues before and after injection of Fe3O4/Na2CO3@PLGA/Cy5.5/cRGD NPs. b Average signal intensity in muscle and tumor for injection of Fe3O4/Na2CO3@PLGA/Cy5.5/cRGD NPs. c T2-MR images on axial and coronal of MDA-MB-231 tumor-bearing mice before and after intravenous injection of Fe3O4/Na2CO3@PLGA/Cy5.5/cRGD NPs. d Signal intensity ratio is calculated by tissue/muscle, tissue stands for the signal intensity of the tumor, liver, and kidney before and after injection of the targeted NPs, muscle stands for the signal intensity of the muscle at the same time