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Table 4 Therapeutic efficacy data of Caelyx® and ED-lip in mice bearing C26 tumor

From: Anti-Epcam Aptamer (Syl3c)-Functionalized Liposome for Targeted Delivery Of Doxorubicin: In Vitro And In Vivo Antitumor Studies in Mice Bearing C26 Colon Carcinoma

Groups

TTEa (day ± SD)

TGDb (%)

MSTc (Day)

PBS

26.146 ± 6.2

0

29.6

Caelyx®

41.102 ± 8.6

68.68

44.1

ED-lip

49.749 ± 2.2

90.27

Undefinedd

  1. a Time to reach end-point
  2. b Tumor growth delay (in comparison with buffer group)
  3. c Median survival time
  4. d Due to complete curing of 3 mice in ED-lip group it is not possible to calculate MST for this group and reported as undefined

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