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Fig. 2 | Nanoscale Research Letters

Fig. 2

From: RETRACTED ARTICLE: microRNA-18a from M2 Macrophages Inhibits TGFBR3 to Promote Nasopharyngeal Carcinoma Progression and Tumor Growth via TGF-β Signaling Pathway

Fig. 2

MiR-18a is highly expressed and TGFBR3 is poorly expressed in NPC cells. a miRanda predicted miR-18a targeting TGFBR3. b Dual luciferase reporter gene assay verified miR-18a targeting TGFBR3. c miR-18a expression was elevated and TGFBR3 expression was decreased in miR-18a mimics-transfected M2 macrophages. d miR-18a expression was decreased and TGFBR3 expression was elevated in miR-18a inhibitors-transfected M2 macrophages. e miR-18a expression was elevated and TGFBR3 expression was decreased in NPC cell lines versus to NP96 cells. f miR-18a expression was elevated and TGFBR3 expression was decreased in miR-18a mimics-transfected SUNE-1 cells. g miR-18a expression was decreased and TGFBR3 expression was elevated in miR-18a inhibitors-transfected CNE2 cells. h miR-18a expression was elevated and TGFBR3 expression was decreased in SUNE-1 cells co-cultured with miR-18a mimics-transfected M2 macrophages. i miR-18a expression was decreased and TGFBR3 expression was elevated in CNE2 cells co-cultured with miR-18a inhibitors-transfected M2 macrophages; *P < 0.05; **P < 0.01. Measurement data were expressed as mean ± standard deviation, N = 3. Comparisons between two groups were analyzed by t test. Comparisons among multiple groups were analyzed by one-way ANOVA, followed by Tukey’s post hoc test

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