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Fig. 6 | Nanoscale Research Letters

Fig. 6

From: M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-κB Signaling Pathway

Fig. 6

M1 macrophage exosomal miR-326 declines CD206 and NF-κB expression in HCC cells. a RT-qPCR detected the effect of transfection of miR-326 mimic on the expression of CD206 and NF-κB in HepG2 cells; b RT-qPCR detected the effect of transfection of miR-326 inhibitor on the expression of CD206 and NF-κB in SMMC-7721 cells. c RT-qPCR detected the effect of co-culture with miR-326 mimic-transfected M1 macrophage-derived exosomes on the expression of CD206 and NF-κB in HepG2 cells; d RT-qPCR detected the effect of co-culture with miR-326 inhibitor-transfected M1 macrophage-derived exosomes on the expression of CD206 and NF-κB in SMMC-7721 cells. In panel a, *P < 0.05 versus the NC-mimic group; In panel b, *P < 0.05 versus the NC-inhibitor group; In panel c, *P < 0.05 versus the control group, #P < 0.05 versus the Exo-NC-mimic group; In panel d, *P < 0.05 versus the control group, #P < 0.05 versus the Exo-NC-inhibitor group. Measurement data were depicted as mean ± standard deviation (N = 3), comparisons among multiple groups were conducted by one-way analysis of variance

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