Fig. 5

Lowly expressed SOX2 and lowly expressed CCAT1 decrease FOXP3 expression and increase miR-185-3p expression in CD44⁺HeLa cells. a SOX2/CCAT1/miR-185-3p/FOXP3 expression in the sh-SOX2 NC and sh-SOX2 groups. b SOX2/CCAT1/miR-185-3p/FOXP3 expression in the sh-CCAT1 NC and sh-CCAT1 groups. c SOX2/CCAT1/miR-185-3p/FOXP3 expression in the mimic NC and miR-185-3p mimic groups. d SOX2/CCAT1/miR-185-3p/FOXP3 expression in the sh-CCAT1 + inhibitor NC and sh-CCAT1 + miR-185-3p inhibitor groups. a p < 0.05 vs. the sh-SOX2 NC group. b p < 0.05 vs. the sh-CCAT1 NC group. c p < 0.05 vs. the mimic NC group. d p < 0.05 vs. the sh-CCAT1 + inhibitor NC group. Measurement data were depicted as mean ± standard deviation, and comparisons among multiple groups were assessed by one-way ANOVA followed by Tukey’s post hoc test