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Table 1 Physical and chemical characteristics of NPs

From: hGC33-Modified and Sorafenib-Loaded Nanoparticles have a Synergistic Anti-Hepatoma Effect by Inhibiting Wnt Signaling Pathway

Co-polymer

Particle size (nm)

PDI

Zeta potential (mV)

LC(%)

EE(%)

hGC33-SFB-NP

120.2 ± 8.2

0.23 ± 0.14

 − 18.2 ± 2.2

4.8 ± 0.5

68.5 ± 6.7

SFB-NP

109 ± 7.1

0.19 ± 0.12

 − 15.9 ± 2.1

5.3 ± 0.6

85.7 ± 4.3

hGC33-null-NP

105.5 ± 8.4

0.21 ± 0.11

 − 18.5 ± 1.8

  

Null-NP

98.1 ± 6.9

0.18 ± 0.11

 − 15.1 ± 2.5

  
  1. Values are reported as mean ± SEM (n = 3). NP, PEG-b-PLGA nanoparticle; PDI, polydispersity index; EE%, encapsulation efficiency %; LC%, drug loading %

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