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Fig. 3 | Nanoscale Research Letters

Fig. 3

From: Targeted Single-Walled Carbon Nanotubes for Photothermal Therapy Combined with Immune Checkpoint Inhibition for the Treatment of Metastatic Breast Cancer

Fig. 3

Serum cytokine concentration. Quantification of serum cytokine levels in mouse serum 7 days after PTT showed a significant increase of IL-6, IFN-γ, and TNF-α levels in mice following PTT in conjunction with check-point inhibition (anti-CTLA-4). The results are shown for the untreated control, SWCNT treatment only, anti-CTLA-4 treatment only, PTT treatment, and PTT + anti-CTLA-4 treatment. Data are presented as mean ± SE (n = 4–5). Statistical significance was analyzed for the treated groups compared to the untreated control group by one-way ANOVA with Dunnett's multiple comparisons test. Statistical significance is indicated by * (p < 0.05) and **** (p < 0.0001)

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