Fig. 4

Inhibition effects and survival curve of BEZ235 or BEZ235-loaded NPs administration. a Inhibition effects of BEZ235 or BEZ235-loaded NPs at different concentrations and administered for 24 h in the HepG2 cell line. b Survival curve of BEZ235 or BEZ235-loaded NPs administration. Each value represents the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01 versus BEZ235, NP-BEZ235, or control group