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Fig. 8 | Nanoscale Research Letters

Fig. 8

From: RETRACTED ARTICLE: The PI3K/mTOR dual inhibitor BEZ235 nanoparticles improve radiosensitization of hepatoma cells through apoptosis and regulation DNA repair pathway

Fig. 8

The role of NP-BEZ235-Ab in the PI3K/AKT/mTOR pathway in of HepG2 cells. a Western blots were performed, using antibodies to PI3K/AKT/mTOR pathway proteins and cyclin-related regulatory protein, with β-actin as a loading control. NP-BEZ235-Ab inhibits PI3K/Akt/mTOR pathway more than does BEZ235. b Diagram of the hypothetical effects of NP-BEZ235-Ab on the PI3K/Akt/mTOR pathway in HepG2 cells. c Cell cycle distribution of HepG2 cells in the flow cytometric analysis of HepG2 cells in each group for 24 h. The data represent three independent experiments

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