Fig. 3
Inhibition of either HDAC1 or miR-124-5p attenuates pathological hippocampus damage and up-regulates neurotransmitter expression in depressed rats. a HE staining of hippocampal lesions of depressed rats; b ELISA of NE expression in hippocampal tissues; c ELISA of 5-HT expression in hippocampal tissues; d ELISA of DA expression in hippocampal tissues; n = 6; a P < 0.05 compared with the normal group; b P < 0.05 compared with the sh-NC group; c P < 0.05 compared with the anti-miR-NC group. Comparisons among multiple groups were evaluated by one-way ANOVA, and pairwise comparisons by Tukey’s post hoc test