Fig. 5

HDAC1 mediates miR-124-5p to regulate NPY. a HDAC1, miR-124-5p and NPY mRNA expression in hippocampal tissues after inhibition of HDAC1 by RT-qPCR (n = 6); b HDAC1 and NPY protein expression in hippocampal tissues after inhibition of HDAC1 by western blot analysis (n = 6); c MiR-124-5p and NPY mRNA expression in hippocampal tissues after inhibition of miR-124-5p by RT-qPCR (n = 6); d NPY protein expression in hippocampal tissues after inhibition of miR-124-5p by western blot analysis (n = 6); a P < 0.05 compared with the normal group; c P < 0.05 compared with the sh-NC group. Comparisons among multiple groups were evaluated by one-way ANOVA, and pairwise comparisons by Tukey’s post hoc test