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Table 4 Typical NPs platforms used in cryosurgery

From: Nanoparticles: A New Approach to Upgrade Cancer Diagnosis and Treatment

NPs

Size (nm)

Thermal conductivity (W/m K)

Heat capacity (J/m3 K)

Benefits

Ref

PCM NPs

10–20

0.35

2.56 × 106

Health tissue protection

[76]

Fe3O4 NPs

8–14

7.1

3.2 × 106

More intracellular ice formation

High thermal conductivity

[77]

Au NPs

3

297.7

2.2 × 106

Good biological compatibility

High thermal conductivity

[78]

HCPN-CG NPs

103.9 ± 1.5

None

None

Cold-responsive nanoparticle for controlled drug release

NIR-induced photothermal effect

[79]

MgO NPs

50

34.3

3.2 × 106

Nontoxic, biodegradable, and few side-effects

[74]

  1. HCPN-CG H for hyaluronic acid, C for chitosan, P for PF127, N for PNIPAM-B, C for CPT, and G for ICG, PCM phase change materials

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