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Fig. 6 | Nanoscale Research Letters

Fig. 6

From: Fe(II) and Tannic Acid-Cloaked MOF as Carrier of Artemisinin for Supply of Ferrous Ions to Enhance Treatment of Triple-Negative Breast Cancer

Fig. 6

a Inhibitors DFO (deferoxamine), Fer-1 (Ferrostatin-1) and Z-VAD-FMK rescued the viability of MDA-MB-231 cells under treatment with 100 μg/mL TA-Fe/ART@ZIF nanoparticles, respectively. b ART, TA-Fe/ZIF, and TA-Fe/ART@ZIF nanoparticles contributed to excessive MDA in MDA-MB-231 cells. c ART, TA-Fe/ZIF, and TA-Fe/ART@ZIF nanoparticles consumed intracellular GSH. d The expression levels of GPX4 proteins in MDA‐MB‐231 cells treated with ART, TA-Fe/ZIF, and TA-Fe/ART@ZIF nanoparticles

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